Evidence also suggests frontal-lobe involvement in MMN generation, perhaps the involuntary switching of attention due to a stimulus change, with thalamic and hippocampal generation of possible MMN subcomponents . Event-related potentials and cognition: A critique of the context updating hypothesis and an alternative interpretation of P3.
The effects of variant auditory stimulus conditions as intensity, presentation rates, and location on the MMN component have been studied extensively.
Picton et al., in an excellent review, note that since the MMN is generated regardless of attention to stimuli, it likely represents an automatic novelty-sensing process .
Additionally, a posterior negativity has been observed in response to alteration of visual stimuli, and has been proposed to be a visual counterpart to the auditory MMN, dubbed v MMN and appearing approximately 120-200 msec post-stimulus .
In addition, MMN latencies have been found to increase with increased standard-deviant intensity deflections, reflecting an elevated cognitive processing requirement for more extensive stimulus deviations .
Keywords: Electroencephalography (EEG), N2, Neuroimaging, P3, Selective attention The widespread adoption of electroencephalography (EEG) for the non-invasive assessment of cortical activity has inaugurated a distinct era in the elucidation of brain function.
Due to its high temporal resolution, EEG imaging of relative scalp electrical positivities and negativities may expose subtle cognitive activity.
Characterization of N200 and P300: Selected Studies of the Event-Related Potential. Two components of the ERP which bear special importance to stimulus evaluation, selective attention, and conscious discrimination in humans are the P300 positivity and N200 negativity, appearing 300 ms and 200 ms post-stimulus, respectively. The relationship of age, gender, handedness, and sidedness to the size of the corpus callosum.
Available from Event-Related Potential (ERP) is a time-locked measure of electrical activity of the cerebral surface representing a distinct phase of cortical processing.